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Will Cialis be prescription or OTC over-the-counter? Call your doctor for medical advice about side effects. Patients who demonstrate hemodynamic instability on alpha-blocker therapy alone are at increased risk of symptomatic hypotension with concomitant use of PDE5 inhibitors. The safety and effectiveness of Cialis when used with other treatments for impotence has not been studied. CIALIS for Use as Needed for ED In eight primary placebo-controlled clinical studies of 12 weeks duration, mean age was 59 years range 22 to 88 and the discontinuation rate due to adverse events in patients treated with tadalafil 10 or 20 mg was 3. You can report an adverse event either online, by regular mail or by fax, using the contact information at the bottom of this page. In such circumstances, nitrates should still only be administered under close medical supervision with appropriate hemodynamic monitoring.The most common side effects with Cialis are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Men who get back pain and muscle aches usually get it 12 to 24 hours after taking Cialis. Back pain and muscle aches usually go away within 2 days. Cialis usually takes about 30 minutes to take effect with sexual stimulation and its effect lasts for up to 36 hours, which is why it is sometimes referred to as a “weekend pill”. Talk with your doctor. You may need to try a different erectile dysfunction medication, such as Viagra, or Levitra. It is possible that a different drug will be. CIALIS for Use as Needed. Creatinine clearance 30 to 50 mL/min: A starting dose of 5 mg not more than once per day is recommended, and the maximum dose is 10 mg not more than once in every 48 hours. Creatinine clearance less than 30 mL/min or on hemodialysis: The maximum dose is 5 mg not more than once in every 72 hours [see .